Figure 4.
MMP-2 and MMP-9 gelatinase activities in the presence of ALA, AUR, and ALA/AUR. U87 cells were treated with 0.2 mM AUR, 0.4 mM AUR, 12.5 mM ALA, or the AUR (0.2 mM)/ALA (12.5 mM) combination for 24 h. The proteolytic activity of MMPs was analyzed using the gelatin zymography method. Data are presented as the mean ± SD. ∗∗∗p value <0.001, ∗∗∗∗p value <0.0001 compared to the control group, and ####p < 0.0001 compared to the ALA/AUR combination.