Table 2.

Changes in central retinal thickness and best-corrected visual acuity in the whole cohort.

	Loading phase (monthly injection)					Maintenance phase (PRN regimen)
	Baseline	1 mo	2 mo	3 mo	4 mo	5 mo	6 mo	7 mo	8 mo	9 mo	10 mo	11 mo	12 mo
CRT (μm, mean ± SD)	486.87 ± 95.46	366.57 ± 75.54	338.30 ± 75.25	329.00 ± 57.49	331.27 ± 73.24	334.90 ± 69.47	390.74 ± 137.23	377.15 ± 110.89	390.45 ± 130.69	368.98 ± 58.81	391.00 ± 52.83	414.30 ± 97.49	382.00 ± 72.02
p value		0.021∗	0.028∗	0.014∗	0.014∗	0.011∗	0.042∗	0.022∗	0.010∗	0.010∗	0.036∗	0.168	0.012∗
BCVA (LogMAR, mean ± SD)	0.51 ± 0.30	0.41 ± 0.27	0.38 ± 0.28	0.36 ± 0.27	0.34 ± 0.24	0.35 ± 0.25	0.37 ± 0.26	0.36 ± 0.24	0.37 ± 0.26	0.39 ± 0.32	0.43 ± 0.18	0.38 ± 0.20	0.35 ± 0.23
p value		0.554	0.510	0.186	0.039∗	0.049∗	0.282	0.153	0.313	0.061	0.369	0.088	0.028∗

^∗Statistically significant difference (p < 0.05), compared with preoperative values in repeated measures ANOVA. CRT: central retinal thickness; BCVA: best-corrected visual acuity; PRN: pro re nata; SD: standard deviation; mo: month.