Table 1.
Prevalence of CRKP carrying two carbapenemases from 1980 to 2022.
|
∼2010 (n = 1001)a |
2011 (n = 735) |
2012 (n = 1032) |
2013 (n = 1969) |
2014 (n = 2766) |
2015 (n = 2290) |
2016 (n = 2904) |
2017 (n = 2855) |
2018 (n = 2874) |
2019 (n = 1591) |
2020 (n = 544) |
2021∼ (n = 455) |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| blaNDM and blaOXA-48-like | 0 | 1 | 3 | 16 | 31 | 60 | 180 | 101 | 101 | 126 | 22 | 24 |
| blaNDM and blaKPC | 0 | 0 | 0 | 1 | 0 | 4 | 6 | 18 | 20 | 24 | 10 | 20 |
| blaKPC and blaOXA-48-like | 0 | 0 | 0 | 2 | 3 | 7 | 1 | 2 | 0 | 9 | 2 | 0 |
| blaKPC and blaVIM | 4 | 2 | 3 | 4 | 3 | 0 | 0 | 1 | 3 | 0 | 2 | 0 |
| blaNDM and blaIMP | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 1 | 0 | 0 |
| blaNDM and blaVIM | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 0 |
| blaVIM and blaOXA-48-like | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
| blaKPC and blaIMP | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
| blaVIM and blaIMP | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| blaIMP and blaOXA-48-like | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Total | 4 | 4 | 6 | 24 | 41 | 71 | 189 | 123 | 130 | 160 | 36 | 44 |
| Prevalence of CRKP carrying blaNDM and blaKPC | 0.00 % | 0.00 % | 0.00 % | 0.05 % | 0.00 % | 0.17 % | 0.21 % | 0.63 % | 0.70 % | 1.51 % | 1.84 % | 4.40 % |
| Prevalence of CRKP carrying two carbapenemases | 0.40 % | 0.54 % | 0.58 % | 1.21 % | 1.48 % | 3.10 % | 6.51 % | 4.31 % | 4.52 % | 10.06 % | 6.61 % | 9.67 % |
a
Number of CRKP genome sequences retrieved from the National Center for Biotechnology Information GenBank database by the year.