Fig. 2. Linear Regressions between plasma biomarkers and Aβ PET (in centiloid) in the whole dataset.
A Plasma GFAP was positively associated with Aβ accumulation in the brain in the whole dataset and in the amyloid-positive and amyloid-negative groups, separately. B, C Plasma pTau181 (B) and pTau181 (C) were positively associated with Aβ accumulation in the brain in the whole dataset and in the amyloid-positive groups. D Plasma NfL was not related to Aβ PET in any group. E Plasma Aβ42/40 was negatively associated with Aβ PET in the whole group only. F Regression lines are drawn only if the Spearman’s rho statistic was significant (p < 0.05). Correlation matrix showing the Spearman’s rho coefficients for the associations between the variables considered.
