Table 3.
Grade (percentage), time, cross tabulation, and their significance for OSCC induced in mice.
| Time | Grades | Pearson Chi- Square | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Normal | Necrosis | Dysplasia | Carcinoma in situ | Grade I | Grade II | Grade III | |||
| Start | Intravenous | 2 (8.3) | 2 (8.3) | 8 (33.3) | 10 (41.7) | 2 (8.3) |
X2 = 4.67 P = 0.323 |
||
| Intralesional | 0 | 0 | 8 (33.3) | 14 (58.3) | 2 (8.3) | ||||
| Total | 2 | 2 | 16 | 24 | 4 | ||||
| Final | Intravenous | 2 (8.3) | 4 (16.7) | 6 (25) | 10 (41.7) | 2 (8.3) |
X2 = 29.14 P < 0.001* |
||
| Intralesional | 12 (50) | 12 (50) | 0 | 0 | 0 | ||||
| Total | 14 | 16 | 6 | 10 | 2 | 48 | |||
It shows statistically significant difference between different grades of OSCC at final assessment with 50% of intralesional have normal and 50% necrosis. However higher grades are detected for intravenous with 41.7% of intravenous are carcinoma in situ, 25% dysplasia, 16.7% necrosis, and 8.3% grade 1.