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. 2023 Jul 25;13:269. doi: 10.1038/s41398-023-02564-6

Fig. 3. Correlation analysis of heme-related subfamily with spleen weight and pro-inflammatory cytokines.

Fig. 3

A–C: There was a positive correlation between Alas2 mRNA and spleen weight (A: R = 0.675, P < 0.001), plasma IL-6 (B: R = 0.486, P = 0.006), or plasma TNF-α (C: R = 0.469, P = 0.008). D, E There were no correlations between Fech mRNA and spleen weight (D; R = 0.270, P = 0.142) or plasma IL-6 (E: R = 0.294, P = 0.109). F There was a correlation between Fech mRNA and plasma TNF-α (F: R = 0.399, P = 0.026). G, H There were positive correlations between Hmbs mRNA and spleen weight (G: R = 0.610, P < 0.001) or plasma IL-6 (H: R = 0.374, P = 0.038). I There was no correlation between Hmbs mRNA and plasma TNF-α (I: R = 0.343, P = 0.058). We used the data of spleen weight, plasma IL-6 and TNF-α from our previous study [37].