Table 3.

Performance of the selected miR ratios on small-RNA sequencing data.

	Strategy 1	Strategy 2
AUC in the original sample
miR-335-5p_let-7f.-5p-2	0.76
miR-199a-3p-2_let-7a-5p-2	0.71
miR-199a-3p-2_let-7f.-5p-2	0.72
let-7a-5p-2_miR-22-3p	0.81
let-7a-5p-2_miR-320a	0.80
let-7f.-5p-1_miR-19b-3p-1	0.79
miR-27a-3p_miR-122-5p	0.71
let-7f.-5p-2_miR-146a-5p	0.78
miR-15b-5p_miR-16-5p-1	0.71
miR-26b-5p_miR-142-5p		0.68
let-7a-5p-2_miR-106b-5p		0.77
let-7f.-5p-1_miR-103a-1		0.76
let-7f.-5p-2_miR-103a-2		0.74
miR-93-5p_miR-19b-3p-1		0.69
miR-22-3p_miR-19b-3p-2		0.67
miR-101-3p-2_miR-19b-3p-1		0.68
miR-30d-5p_miR-20a-5p		0.68
let-7b-5p_miR-19b-3p-1		0.74
miR-15a-5p_miR-16-5p-2		0.66
miR-20a-5p_miR-19b-3p-1		0.77
miR-21-5p_miR-23a-3p		0.68
Performance of the strategies by fivefold cross-validation
Calibration intercept	0.051	0.024
Calibration slope	1.269	0.840
Scaled brier	0.060	0.060
AUC	0.797	0.791

AUC: area under the ROC curve.