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. 2023 Jul 25;6:775. doi: 10.1038/s42003-023-05143-z

Table. 1.

Correlation between NFIB expression and clinicopathological features in cancer tissues from 261 CRC patients.

Features No. of patients (%) NFIB level P value
Low (n = 131) No. (%) High (n = 130) No. (%)
Gender
  Male 153(58.6%) 83(54.2%) 70(45.8%) 0.119
  Female 108(41.4%) 48(44.4%) 60(55.6%)
Age
  ≤60 131(50.2%) 73(55.7%) 58(44.3%) 0.073
  >60 130(49.8%) 58(44.6%) 72(55.4%)
NAMPT level
  Low 168(64.4%) 92(54.8%) 76(45.2%) 0.047
  High 93(35.6%) 39(41.9%) 54(58.1%)
Vascular invasion
  Yes 99(37.9%) 51(51.5%) 48(48.5%) 0.738
  No 162(62.1%) 80(49.4%) 82(50.6%)
Nerve invasion
  Yes 57(21.8%) 30(52.6%) 27(47.4%) 0.677
  No 204(78.2%) 101(49.5%) 103(50.5%)
Differentiation degree
  Well 69(26.4%) 38(55.1%) 31(44.9%) 0.06
  Moderate 98(37.5%) 55(56.1%) 43(43.9%)
  Poor 94(36.0%) 38(40.4%) 56(59.6%)
Size (cm)
  ≤4.8 142(54.4%) 74(52.1%) 68(47.9%) 0.498
  >4.8 119(45.6%) 57(47.9%) 62(52.1%)
T stage
  I 8(3.1%) 5(62.5%) 3(37.5%) 0.056
  II 49(18.8%) 32(65.3%) 17(34.7%)
  III 189(72.4%) 89(47.1%) 100(52.9%)
  IV 15(5.7%) 5(33.3%) 10(66.7%)
T stage
  I + II 57(21.8%) 37(64.9%) 20(35.1%) 0.012
  III + IV 204(78.2%) 94(46.1%) 110(53.9%)
N stage
  0 156(59.8%) 87(55.8%) 69(44.2%) 0.06
  1 65(24.9%) 25(38.5%) 40(61.5%)
  2 40(15.3%) 19(47.5%) 21(52.5%)
N stage
  Negative 156(59.8%) 87(55.8%) 69(44.2%) 0.028
  Positive 105(40.2%) 44(41.9%) 61(58.1%)
Distant metastasis
  Negative 256(98.1%) 129(50.4%) 127(49.6%) 0.684
  Positive 5(1.9%) 2(40.0%) 3(60.0%)
TNM stage
  I 50(19.2%) 33(66.0%) 17(34.0%) 0.042
  II 104(39.8%) 53(51.0%) 51(49.0%)
  III 102(39.1%) 43(42.2%) 59(57.8%)
  IV 5(1.9%) 2(40.0%) 3(60.0%)
TNM stage
  I + II 154(59.0%) 86(55.8%) 68(44.2%) 0.028
  III + IV 107(41.0%) 45(42.1%) 62(57.9%)