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. 2023 Jul 11;5:100161. doi: 10.1016/j.crphar.2023.100161

Fig. 6.

Fig. 6

Apigenin reversed cell damage in the hippocampal brain regions and prefrontal cortex of CUMS-induced mice. (A) Effect of apigenin on the expressions of healthy cells on the histoarchitecture of the CA1, CA3, dentate gyrus and the prefrontal cortex of CUMS-induced mice after staining with H and E. (B) The population of healthy cells in the CA1 of mice brains after pretreatment with apigenin in CUMS-induced mice (C) The population of healthy cells in the CA3 of mice brains after pretreatment with apigenin in CUMS-induced mice (D) Population of healthy cells in the dentate gyrus of mice brains after pretreatment with apigenin in CUMS-induced mice (E) The population of healthy cells in the prefrontal cortex of mice brains after pretreatment with apigenin in CUMS-induced mice. Scale bar = 320 μm (n = 10, **P < 0.01, ***P < 0.01 and ****P < 0.0001 v control; **P < 0.01, ****P < 0.0001 v stress). Data expressed as mean ± SD. One-way analysis of variance (ANOVA) followed by Tukey's multiple comparison test.