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. 2023 Jul 11;5:100161. doi: 10.1016/j.crphar.2023.100161

Fig. 7.

Fig. 7

Apigenin inhibited monoamine oxidase A inhibitory enzymatic activity in the hippocampal brain regions and prefrontal cortex of CUMS-induced mice (A) Inhibitory effect of apigenin on the expressions of MAOA immunoreactive positive cells in the CA1, CA3, dentate gyrus and prefrontal cortex of CUMS-induced mice after immunohistochemistry (B) Inhibitory effect of apigenin on the density of MAOA immunoreactive positive cells in the CA1 of CUMS-induced mice (C) Inhibitory effect of apigenin on the density of MAOA immunoreactive positive cells in the CA3 of CUMS-induced mice (D) Inhibitory effect of apigenin on the density of MAOA immunoreactive positive cells in the dentate gyrus of CUMS-induced mice (E) Inhibitory effect of apigenin on the density of MAOA immunoreactive positive cells in the prefrontal cortex of CUMS-induced mice. Scale bar = 320 μm (n = 10, ***P < 0.001, ****P < 0.0001 v control; **P < 0.01, ****P < 0.0001 v stress). Data expressed as mean ± SD. One-way analysis of variance (ANOVA) followed by Tukey's multiple comparison test.