Table 1.

Allele and genotype frequencies of SNPs evaluated in the whole series

		Whole population		LEN arm		OBS arm		P	chi2
		MAF	HWE	MAF	HWE	MAF	HWE
ABCB1	c.1236	0.444	0.881	0.436	0.113	0.448	1.811	.484	1.454
ABCB1	c.2677	0.428	1.464	0.426	0.283	0.422	2.923	.680	0.771
ABCB1	c.3435	0.491	0.236	0.485	0.008	0.521	0.181	.732	0.625
VEGF	c.2055	0.563	0.499	0.559	0.421	0.526	0.994	.439	1.645
ABCG2	c.421	0.939	0.002	0.926	0.56	0.964	0.137	.157	2.000
FCGR2A	c.497	0.404	0.459	0.411	0.641	0.389	1.082	.400	1.834
NCF4	−368	0.359	0.108	0.401	0.532	0.316	0.525	.266	2.652
GSTP1	313	0.327	0.237	0.317	1.730	0.300	0.048	.660	0.831
CRBN	rs1714327	0.285	1.046	0.292	1.316	0.268	1.268	.817	0.404
CRBN	rs1705814	0.428	29.977	0.426	13.563	0.379	5.456	.390	1.885

HWE, Hardy-Weinberg equilibrium; MAF, minor allele frequency.