Fig. 1.
Oral administration of pasteurized A. muciniphila improves body weight during a HFD45%. Effects of an oral administration of vehicle or pasteurized A. muciniphila on (A) body weight gain evolution over time, *p < 0.05, **p < 0.01, ****p < 0.0001 vs HFD Vehicle, (B) body weight at the beginning of the protocol (D0), no significant difference was observed, (C) body weight gain at week 12 of treatment, **p < 0.01 vs HFD Vehicle, (D) food intake, ****p < 0.0001 vs HFD Vehicle, (E) Total fat mass ***p < 0.001 vs HFD Vehicle, (F) Adipose tissue index, ***p < 0.001 vs HFD Vehicle, (G) Subcutaneous adipose tissue (SAT), **p < 0.01 vs HFD Vehicle, (H) Visceral adipose tissue (VAT), **p < 0.01 vs HFD Vehicle, (I) Epididymal adipose tissue (EAT), ***p < 0.001 vs HFD Vehicle, (J) Brown adipose tissue (BAT), no significant difference was observed. The associated p-values obtained using an unpaired t-test. n = 8–10 per group.
