Table 2.
Clinical outcomes | Median (range) or N (%) |
---|---|
Best response to CAR-T | |
CR | 56 |
PR/VGPR | 24 |
SD | 5 |
PD | 14 |
Not assessed | 1 |
CRS | 76 |
CRS grade | |
1 | 50 |
2 | 25 |
3 | 0 |
4 | 1 |
5 | 0 |
ICANS | 33 |
ICANS grade | |
1 | 14 |
2 | 9 |
3 | 7 |
4 | 0 |
5 | 3 |
Received corticosteroids for CRS and/or ICANS | 40 |
Follow-up time from CAR-T infusion, median (range), mo | 14 (0.4-36) |
Alive at the time of data cutoff | 62 |
Index CAR-T hospitalization length of stay, median (range), d | 14.5 (4-47) |
Hospital readmission within 6 mo of CAR-T infusion | 41 |
ICU admission within 6 mo of CAR-T infusion | 9 |
Overall survival, median (range), mo | NR (95% CI, 20.3-NR) |
CR, complete response; NR, not reached; PD, progressive disease; PR, partial response; SD, stable disease; VGPR, very good partial response.