Table 1.
Treatment | N | Tumor Volume (mm3) at day31 | Complete Response Rate at Day 52 |
---|---|---|---|
PBS | 5 | 1496.03 ± 78.62 | 0/5 |
empty LNP | 5 | 1345.98 ± 216.05 | 0/5 |
Luc mRNA_10 μg (1 dose) | 5 | 1624.89 ± 113.18 | 0/5 |
HPV mRNA_10 μg (1 dose) | 5 | 34.20 ± 17.73 | 2/5 |
HPV mRNA_3 μg (1 dose) | 5 | 82.32 ± 43.80 | 1/5 |
Luc mRNA_10 μg (2 dose) | 5 | 1507.73 ± 152.09 | 0/5 |
HPV mRNA_10 μg (2 dose) | 5 | 12.29 ± 8.27 | 2/5 |
HPV mRNA_3 μg (2 doses) | 5 | 22.76 ± 15.88 | 1/5 |
N= number of animals per group.