Table 1.

Instrumental variables used in MR analysis of the association between psoriasis and CM.

exposure	SNP	Effect allele	Other allele	MAF	F	R2 of exposure	Exposure (psoriasis)			Outcome (CM)
							Beta	SE	P-value	Beta	SE	P-value
psoriasis	rs10193310	A	G	0.248	55.501	0.006	0.127	0.017	9.341E-14	0.054	0.166	0.747
psoriasis	rs12206050	T	A	0.320	41.025	0.004	0.101	0.016	1.502E-10	-0.006	0.154	0.970
psoriasis	rs1250566	A	G	0.408	33.638	0.004	-0.089	0.015	6.639E-09	-0.111	0.146	0.448
psoriasis	rs13153019	C	T	0.273	38.114	0.004	0.102	0.016	6.673E-10	-0.033	0.162	0.836
psoriasis	rs139298380	A	G	0.028	56.899	0.005	0.313	0.042	4.589E-14	0.365	0.442	0.409
psoriasis	rs144651842	A	G	0.078	40.923	0.004	0.172	0.027	1.584E-10	-0.070	0.271	0.796
psoriasis	rs1611704	T	C	0.345	217.349	0.023	0.225	0.015	3.426E-49	-0.120	0.153	0.433
psoriasis	rs16903065	A	C	0.116	34.184	0.004	-0.141	0.024	5.014E-09	-0.317	0.226	0.161
psoriasis	rs181316459	C	G	0.047	102.654	0.010	0.330	0.033	3.992E-24	-0.629	0.354	0.076
psoriasis	rs2021511	T	C	0.265	40.027	0.005	-0.109	0.017	2.505E-10	-0.219	0.162	0.176
psoriasis	rs2769979	C	T	0.605	39.928	0.004	-0.096	0.015	2.635E-10	0.025	0.146	0.862
psoriasis	rs28732090	G	C	0.058	1018.007	0.070	0.798	0.025	1.000E-200	0.735	0.308	0.017
psoriasis	rs28998802	A	G	0.184	73.995	0.008	0.161	0.019	7.834E-18	-0.168	0.185	0.362
psoriasis	rs33980500	T	C	0.072	78.437	0.008	0.238	0.027	8.260E-19	-0.232	0.278	0.404
psoriasis	rs34536443	C	G	0.030	35.369	0.005	-0.282	0.047	2.728E-09	-0.692	0.418	0.098
psoriasis	rs34955377	A	G	0.116	83.401	0.008	0.202	0.022	6.697E-20	0.159	0.223	0.475
psoriasis	rs4400255	A	T	0.099	58.398	0.006	0.181	0.024	2.140E-14	-0.016	0.241	0.947
psoriasis	rs60600003	G	T	0.102	39.937	0.004	0.150	0.024	2.623E-10	-0.167	0.237	0.480
psoriasis	rs653169	G	A	0.570	32.578	0.004	-0.086	0.015	1.145E-08	0.025	0.146	0.862
psoriasis	rs6556423	T	C	0.642	139.728	0.015	-0.180	0.015	3.054E-32	-0.152	0.150	0.310
psoriasis	rs674451	C	T	0.344	68.473	0.007	0.128	0.015	1.286E-16	0.158	0.150	0.294
psoriasis	rs7310615	G	C	0.586	32.924	0.004	-0.087	0.015	9.584E-09	-0.119	0.145	0.414
psoriasis	rs74817271	A	G	0.074	70.719	0.007	0.225	0.027	4.119E-17	-0.128	0.272	0.636
psoriasis	rs7542079	C	T	0.562	39.763	0.004	0.095	0.015	2.867E-10	-0.084	0.144	0.563
psoriasis	rs76741620	G	A	0.058	32.732	0.003	0.174	0.030	1.058E-08	-0.120	0.308	0.696
psoriasis	rs78456138	T	C	0.020	38.134	0.005	-0.365	0.059	6.606E-10	0.830	0.513	0.106
psoriasis	rs80174646	T	G	0.046	35.310	0.005	-0.227	0.038	2.812E-09	0.174	0.350	0.619
psoriasis	rs847	C	T	0.635	64.721	0.007	0.127	0.016	8.628E-16	0.158	0.150	0.292
psoriasis	rs8904	A	G	0.388	66.919	0.008	-0.126	0.015	2.829E-16	0.002	0.147	0.992
psoriasis	rs9273060	T	A	0.249	174.059	0.018	0.219	0.017	9.618E-40	-0.110	0.168	0.512
psoriasis	rs9346778	T	C	0.164	31.988	0.004	-0.117	0.021	1.551E-08	-0.030	0.192	0.875