FIGURE 6.

PRx as measure for cerebral autoregulation following fluid injection: the pressure reactivity index PRx, for assessment of cerebral autoregulation (CA) was calculated as the continuous Pearson correlation coefficient between intracranial pressure and arterial blood pressure at low frequencies. PRx > 0.2 indicates impaired CA, whereas PRx < 0.2 points toward an intact CA. (A) Median of PRx time courses for all groups. (B) Quantitative analysis at distinct time points (**p < 0.01; *p < 0.05). (C) Distribution between categories of mostly (more than 50% of the datapoints are > 0.2) or transiently (less than 50% but more than 0% of all datapoints are > 0.2) impaired or intact (0% of the datapoints are > 0.2, means all datapoints are < 0.2) CA according to the cutoff value of PRx 0.2 (% of animals in each group).