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. 2023 Jul 3;26(8):107270. doi: 10.1016/j.isci.2023.107270

Figure 2.

Figure 2

A subset of cancer cells demonstrates pseudo-regular responses to acetylcholine stimulation

(A) Representative examples of Ca2+ traces of “regular responders” – cancer cell lines which, similarly to HEK293 cells, have a significant number of cells with a correlation between the peak onset and agonist exposure.

(B–E) Residual distribution dependence of the average response height for regularly responding cancer cell lines is extremely variable and cell line-dependent. Shown are cancer cells of the hepatocellular carcinoma SNU398 (B), HEP3B (C), and HUH7 (D) cell lines, and the colorectal cancer cell line LS174T (E).