Fig. 6.

Deviation-scores plotted against the volume of the lesion, with the different colors indicating the different databases used. Each dot is the result of a single patient and database. Solid lines represent the results of an exponential fit, with adjacent shaded areas marking the 95% confidence intervals. The R² in the legend represents the proportion of variance explained by the polynomial fit, adjusted for the number of parameters in the model. The x-axis is truncated at 20 cm³ for clearer visualization, excluding 20 patients from the plot (but not the analysis). The horizontal dashed line at a deviation-score of 1.0 is the reference for a fully realistic estimate of standard deviations provided by the prediction.