Table 4. Overview of baseline characteristics in the included studies.

CLABSI, central line-associated bloodstream infection; GA, gestational age; NR, not reported

Studies	Country	Study design	Year of publication	Sample size	Mean/median age	Gender (male %)
Dipietro et al. [29]	USA	Observational analysis	2020	17,846	NR	NR
Herc et al. [24]	USA	Comparative study	2017	23,088	>65: 11,392; <64: 5,415	NR
Hernández-Aceituno et al. [28]	Spain	Observational analysis	2020	584	G1: 68.0 (12.6); G2: 69.1 (12.4)	NR
Kim et al. [25]	South Korea	Multicenter study	2018	612	Tunneled: 68.0 ± 15.9; conventional: 68.7 ± 14.6	44.4
Lissauer et al. [21]	USA	Comparative study	2012	961	26	NR
Rhee et al. [22]	USA	Observational analysis	2015	104	56.5 ± 14.2 (20–84)	NR
Advani et al. [18]	USA	Comparative study	2010	683	5 (2–8)	56.4
Torre et al. [26]	Brazil	Multicenter study	2018	170	32	57.1
Wong et al. [23]	Australia	Observational analysis	2016	6,353	CLABSI: 54 (36–68); No CLABSI: 61 (46–73)	NR
Stevens et al. [19]	USA	Retrospective cohort study	2013	398	117	62.1
Jeong et al. [32]	South Korea	Case-control study	2021	141	31±5 weeks (GA)	NR
Malek et al. [27]	Egypt	Observational analysis	2018	499	58.2 ± 14.6	72.3
Ahn et al. [30]	South Korea	Observational analysis	2023	2,189	65.0 (54.0–74.0)	58.8
Baier et al. [31]	Germany	Case-control study	2020	610	47	61.5
Khieosanuk et al. [20]	Thailand	cohort study	2021	1,048	0.1 (IQR: 0.03-0.3) months	67.1