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. 2023 Jul 12;14:1168780. doi: 10.3389/fimmu.2023.1168780

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Copyright © 2023 Zhou, Huang, Li, Song, Yang, Wang and Meng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ssGSEA immune infiltration. (A) Heat map of the differences in the distribution of 28 immune cells in each sample. (B) Correlation analysis between 28 immune cell species. (C, D) Violin plots of differences in the infiltration of 28 immune cells and 13 immune functions in normal synovial and OA synovial samples. (E) Box plot of HLA gene expression differences in normal and OA synovial samples. (F, G) Correlation analysis of Hub OA-ARDEGs with 28 immune cells and 13 immune functions, *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.