Table 4.
Parasite loads of heart, liver, lung and spleen from BALB/c mice.
| Group | parasite loads of tissues (×105)a | |||
|---|---|---|---|---|
| heart | liver | lung | spleen | |
| PBS | 1.61±0.17 | 2.78±0.42 | 14.19±0.72 | 0.62±0.05 |
| Alum | 1.57±0.19 | 2.66±0.74 | 14.09±2.13 | 0.47±0.05 |
| PLGA | 1.40±0.10 | 2.50±0.68 | 13.90±0.95 | 0.51±0.04 |
| Alum+GRA7 | 0.43±0.15 b | 0.36±0.09 e | 0.48±0.09 h | 0.01±0.00 k |
| PLGA+GRA7 | 0.34±0.01 b | 0.27±0.04 e | 0.47±0.06 h | 0.01±0.00 k |
| Alum+GRA12 | 0.36±0.10 c | 0.33±0.08 f | 0.56±0.13 i | 0.08±0.01 l |
| PLGA+GRA12 | 0.12±0.02 c, d | 0.13±0.03 f, g | 0.18±0.04 i, j | 0.01±0.00 l, m |
a, the average value and standard deviation represented ×105.
b, c, k, l, compared with PBS, Alum or PLGA, p < 0.001.
d, g, j, compared with Alum+GRA12, p < 0.05.
e, f compared with PBS, Alum or PLGA, p < 0.05.
h, i, compared with PBS, Alum or PLGA, p < 0.01.
m, compared with Alum+GRA12, p < 0.01.