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Fig. 5. AR42J cell uptake of oxidized Tyr3-octreotide peptide tracers [18F]6 and [18F]7 demonstrating specific uptake in both internalized and total cell associated fractions (=internalized + membrane bound) that was blocked by co-incubation of non-modified octreotide. Intern.; internalized, Membr; membrane bound. The data is presented as mean ± standard deviation of cell uptake (%) from the total added radioactivity. Statistical significance *p < 0.05, **p < 0.005, ***p < 0.001, ****p < 0.0001. (Panel A) Internalized fraction. (Panel B) Cell associated = membrane bound and internalized fractions.