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. 2023 Jul 12;14:1128382. doi: 10.3389/fphar.2023.1128382

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Copyright © 2023 Kamga Kapchoup, Hescheler and Nguemo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Multielectrode arrays recordings of spontaneously beating EBs/cardiac cluster and effect of HDQ. (A,B) Microscopy images of mES cells (mESC) colony (A) and EBs (B) at day 14 of differentiation. (C) Viable and spontaneously beating mESC-derived cardiac cluster attached to MEA chamber. (D) Representative extracellular field potential (FP) of beating cluster of miPSC-CMs recordings from all 60 electrodes of MEA plate.