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. 2023 Jul 24;32:09636897231187996. doi: 10.1177/09636897231187996

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — OC organoid have distinct transcriptomes after PARPi treatment. (A) Significantly upregulated and downregulated genes from control and PARPi treatment samples for the RNA sequencing results. (B, C) Gene ontology classification of organoid. Representatively upregulated or downregulated genes closely related molecular function, biological process, and cell components. The size of the bubbles indicates the number of associated genes. (D, E) Significantly changed genes linked base excision repair and cell cycle.