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PARPi reduce cell proliferation and cell cycle in patient-derived organoid. (A, B) Expression level of 6 candidate genes linked to base excision repair pathways or cell cycle pathways after 48 h with different dosages of PARPi (0/50/100 nM) treatment. Data are presented as the mean ± SEM (n = 3; ns, no significance; *P < 0.05; **P < 0.01; ***P < 0.001; student’s test).
