Table 3.
Receiver operating characteristic (ROC) analysis in gastric cancer patients for different tumour size, histological type, histological differentiation grade and Helicobacter pylori infection.
| Parameter | AUC | p-value | Cut-off | Sensitivity (%) | Specificity (%) | 95% confidence interval |
|---|---|---|---|---|---|---|
| Tumour size | ||||||
| NO | 0.7510 | 0.0194 | > 0.6859 | 65.22 | 72.73 | 0.5733 to 0.9287 |
| Nitrotyrosine | 0.7489 | 0.0225 | > 1032 | 66.67 | 63.64 | 0.5633 to 0.9346 |
| Amadori products | 0.7861 | 0.0091 | > 34.14 | 69.23 | 75.00 | 0.6192 to 0.9529 |
| Histological type | ||||||
| Amadori products | 0.7164 | 0.0410 | > 34.03 | 64.00 | 63.64 | 0.5414 to 0.8914 |
| NO | 0.8737 | <0.0001 | > 0.7832 | 78.95 | 75.00 | 0.7657 to 0.9816 |
| Histological differentiation grade | ||||||
| S-nitrosothiols | 0.7229 | 0.0224 | > 74.39 | 64.00 | 64.29 | 0.5645 to 0.8812 |
| Tryptophan | 0.7143 | 0.0273 | > 20.66 | 66.67 | 67.85 | 0.5455 to 0.8831 |
| Helicobacter pylori infection | ||||||
| NO | 0.7596 | 0.0276 | > 1.400 | 61.54 | 66.67 | 0.5610 to 0.9582 |
| Kynurenine | 0.7403 | 0.0428 | > 1674 | 72.73 | 71.43 | 0.5417 to 0.9388 |
| N-formylkynurenine | 0.7500 | 0.0339 | > 1001 | 61.54 | 66.67 | 0.5550 to 0.9450 |
AUC, area under curve; NO, nitric oxide.