Skip to main content
. 2023 May 10;10(20):2207334. doi: 10.1002/advs.202207334

Figure 5.

Figure 5

Adipose‐derived stem cells (ADSCs) increase the survival rate of fat grafts. A) Schematic illustration of the co‐transplantation of fat grafts with phosphate‐buffered saline (PBS), ADSCs transfected with Luciferase (ADSCmodLuc) and ADSCs transfected with VEGF modRNA (ADSCmodVEGF). (a) Representative gross morphological images of fat grafts at 15, 30 and 90 d following transplantation. (b) Representative gross morphological assessment and hematoxylin and eosin (H&E) staining of extracted fat grafts at 1‐week post‐implantation. Yellow arrows indicate new blood vessel formation within the fat grafts. Reproduced under terms of the CC‐BY license.[ 92 ] Copyright 2020, The Authors, Published by Springer Nature. B) Schematic illustration of isolation of CD34+CD146+, CD34+CD146−, and CD34+ unfractionated (UF) ADSCs by fluorescence‐activated cell sorting (FACS). (c) Micro‐computed tomography of fat grafts at 8 weeks post‐transplantation. Reproduced under terms of the CC‐BY license.[ 93 ] Copyright 2020, Oxford University Press. C) Magnetic resonance imaging (MRI) of the same areas of healthy participants before implantation and day 0 and 121 after implantation. Reproduced with permission.[ 94 ] Copyright 2013, Elsevier.