Table 4.
In-hospital mortality and morbidities (composite outcomes) among infants born at 29 to 33 weeks’ GA by maternal IDDM
| Outcome, N (%) | IDDM, N = 527 | No IDDM, N = 6,509 | Adjusted RR (95% CI) for outcomea IDDM vs. no IDDM |
|---|---|---|---|
| Surfactant or death within 3 days | 136/527 (26) | 1733/6,508 (27) | 0.99 (0.86–1.14) |
| EOS or LOS or death before discharge | 28/523 (5) | 393/6,496 (6) | 0.75 (0.48–1.16) |
| Severe IVH or death within 28 days | 18/296 (6) | 206/3,803 (5) | 1.17 (0.70–1.94) |
| PVL (at 28 days or 36 weeks) or death within 28 days | 21/310 (7) | 229/3,939 (6) | 1.16 (0.72–1.86) |
| ROP or death within 28 days | 29/183 (16) | 344/2,370 (15) | 1.23 (0.85–1.78) |
| NEC or death within 28 days | 30/527 (6) | 288/6,504 (4) | 1.18 (0.78–1.79) |
| PDA or death within 28 days | 87/527 (17) | 763/6,505 (12) | 1.46 (1.18–1.80) |
Abbreviations: CI, confidence interval; EOS, early-onset sepsis; GA, gestational age; IBP, insulin before pregnancy; IDP, insulin during pregnancy; IVH, intraventricular hemorrhage; LOS, late-onset sepsis; NEC, necrotizing enterocolitis; No IDDM, no insulin-dependent diabetes mellitus; PDA, patent ductus arteriosus; PVL, periventricular leukomalacia; ROP, retinopathy of prematurity; RR, relative risk.
Note: All models were adjusted for study center, infant gender, gestational age at birth, antenatal steroid use, maternal age, maternal race, prenatal care, multiple births, chorioamnionitis, cesarean delivery, outborn, ponderal index at birth, and delivery room interventions (CPAP vs. other), unless mentioned otherwise.
Poisson regression models with robust variance estimators were used for adjusted analysis of categorical outcomes.