Table 1. aegPNA, Thyclotide, and cpPNA Used in the Melting Experiments.

^aCyclopentane stereochemistry is (S,S), and tetrahydrofuran stereochemistry is (R,R); B* = thf residue, B^# = cp residue. PNA and thyclotide sequences are written from the N- to C-terminal. In each oligomer, 2-aminoethoxy-2-ethoxy acetic acid (AEEA) is the first residue at the C-terminal, and the N-terminal is a free amine.