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. 2023 Jul 5;63(14):4253–4265. doi: 10.1021/acs.jcim.3c00607

Figure 2.

Figure 2

Timeline illustrating the growth in contributors over time for each database. Sources for the data are given in Figure 1. PubChem data on the individual number of contributors over time was not available; thus “sources” (i.e., organizations) are plotted instead. As ChEMBL does not follow a contributor model but an expert curation model, its growth in data sources is plotted instead. Finally, note that, while the CSD follows a contributor model, the submission process also includes manual review by domain experts at the CCDC. Traces do not necessarily start close to 0 due to limited public information for early dates of some efforts.