Table 4.
Genotype and allele distribution of BMP-7 rs230205[A/G] SNP among different groups
| Genotype/allele | Controls (n = 50) | Cirrhosis (n = 50) | P-value | OR [95% CI] | ||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| GG | 35 | 70.0 | 30 | 60.0 | – | 1.0 |
| AG | 11 | 22.0 | 14 | 28.0 | NS | 1.48 [0.59-3.76] |
| AA | 4 | 8.0 | 6 | 12.0 | NS | 1.75 [0.45-6.79] |
| G | 81 | 81.0 | 74 | 74.0 | – | 1.0 |
| A | 19 | 19.0 | 26 | 26.0 | NS | 1.50 [0.77-2.93] |
| Controls (n = 50) | HCC (n = 50) | |||||
| GG | 35 | 70.0 | 28 | 56.0 | – | |
| AG | 11 | 22.0 | 15 | 30.0 | NS | 1.70 [0.68-4.29] |
| AA | 4 | 8.0 | 7 | 14.0 | NS | 2.19 [0.58-8.23] |
| G | 81 | 81.0 | 71 | 71.0 | – | 1.0 |
| A | 19 | 19.0 | 29 | 29.0 | NS | 1.74 [0.90-3.37] |
| Cirrhosis (n = 50) | HCC (n = 50) | |||||
| GG | 30 | 60.0 | 28 | 56.0 | – | 1.0 |
| AG | 14 | 28.0 | 15 | 30.0 | NS | 1.15 [0.47-2.80] |
| AA | 6 | 12.0 | 7 | 14.0 | NS | 1.25 [0.37-4.17] |
| G | 74 | 74.0 | 71 | 71.0 | – | 1.0 |
| A | 26 | 26.0 | 29 | 29.0 | NS | 1.16 [0.62-2.16] |
NS – not significant