Table 5.
Association between laboratory investigations and BMP-7 rs230205 [A/G] genotypes
| rs230205 [A/G] of BMP-7 gene | Test of sig. | P-value | Post hoc test | |||
|---|---|---|---|---|---|---|
| GG (n = 58) | AG (n = 29) | AA (n = 13) | ||||
| Mean ±SD | Mean ±SD | Mean ±SD | ||||
| Hb (g/dl) | 12.0 ±1.0 | 11.6 ±1.1 | 11.7 ±0.7 | 1.58 | 0.210 | P1 = 0.243, P2 = 0.502, P3 = 0.997 |
| Platelets (103/µl) | 135.4 ±36.0 | 133.6 ±48.0 | 142.9 ±48.3 | 0.11 | 0.943 | P1 = 0.918, P2 = 0.732, P3 = 0.796 |
| TLC (103/µl) | 5.1 ±1.8 | 5.1 ±1.9 | 3.9 ±1.1 | 4.45 | 0.108 | P1 = 0.868, P2 = 0.034, P3 = 0.089 |
| Albumin (g/dl) | 3.5 ±0.5 | 3.2 ±0.6 | 3.1 ±0.5 | 4.45 | 0.014* | P1 = 0.045, P2 = 0.062, P3 = 0.982 |
| Total bilirubin (mg/dl) | 1.2 ±0.7 | 1.5 ±0.8 | 1.4 ±0.8 | 3.56 | 0.168 | P1 = 0.072, P2 = 0.363, P3 = 0.531 |
| Direct bilirubin (mg/dl) | 0.5 ±0.4 | 0.7 ±0.6 | 0.6 ±0.5 | 2.12 | 0.346 | P1 = 0.143, P2 = 0.680, P3 = 0.585 |
| ALT (IU/l) | 56.2 ±24.2 | 56.0 ±17.5 | 53.4 ±30.4 | 0.67 | 0.714 | P1 = 0.861, P2 = 0.577, P3 = 0.295 |
| AST (IU/l) | 53.3 ±23.6 | 51.1 ±21.9 | 57.8 ±24.6 | 0.78 | 0.677 | P1 = 0.719, P2 = 0.462, P3 = 0.414 |
| AFP (ng/ml) | 216.2 ±701.7 | 224.0 ±821.1 | 428.5 ±889.0 | 2.03 | 0.361 | P1 = 0.347, P2 = 0.368, P3 = 0.201 |
Hb – hemoglobin, TLC – total leucocyte count, ALT – alanine aminotransferase, AST – aspartate aminotransferase, AFP – α-fetoprotein, * significant, P1 – difference between GG and AG, P2 – difference between GG and AA, P3 – difference between AG and AA