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Nuclear export of mRNP through native (A) and aberrant NPCs (B). Both illustrations show an mRNP particle successfully exporting through the NPC (green arrow) and abortively exporting from the NPC (red arrow). The nuclear basket, central channel, or cytoplasmic fibril subregions separate the abortive nuclear export. The numerical values for the successful and abortive nuclear export indicate the transport efficiency from the 2021 Li et al. study.89
