Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 26;28:255. doi: 10.1186/s40001-023-01200-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 4 — Identifying potential biomarkers for CD. A The SVM-RFE model. The horizontal axis denotes the number of featured genes, while the vertical axis represents the error rate in curve variation after cross-validation. In the graph, N = 4 in the figure indicates that there are 4 feature genes with the lowest error rate, which is close to zero. B The LASSO model. The horizontal axis displays the logarithmic punishment coefficient, log λ, while the vertical axis shows the error of the cross-validation. A lower value on the Y-axis indicates a better fitting result of the equation. The two dashed lines indicate two specific lambda (λ) values. The dashed line on the left represents λ min, which indicates the lambda value when the bias is minimal, signifying that the model fitting is the best at this lambda value. In this study, λ min on the left was chosen as the final criterion for selecting the equation. The dashed line on the right represents λ-se, which refers to one standard error to the right of the minimum λ value; C in colon tissue, LASSO and SVM-RFE share biomarkers