Figure 1.

Distinct cell types in HSCC tissues, adjacent normal tissues and lymphatic tissues identified through integrating single-cell transcriptomic data. (A) Overview of the study design, sample collection, single cell preparation, sequencing, and bioinformatic analysis. (B) Uniform manifold approximation and projection (UMAP) plot showing the clustering of different cell subsets in HSCC tissues, adjacent normal tissues, and lymphatic tissues. (C) Sample cell composition histogram of HSCC tissues, adjacent normal tissues, and lymphatic tissues. (D) Bubble chart of top 5 differential genes in each cell subset.