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. 2023 Jul 12;14:1168191. doi: 10.3389/fimmu.2023.1168191

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Copyright © 2023 Li, Guan, Li, Wei, Cao, Xu, Chang, Wang, Chen and Lei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subpopulations and transcriptome landscape of proliferating lymphocytes and cell exhausted levels in HSCC tissues, adjacent normal tissues, and lymphatic tissues. (A) Uniform manifold approximation and projection (UMAP) plot showing the sub classification of proliferating lymphocytes. (B) Bar charts showing the proportion of each proliferating lymphocytes subtype in HSCC tissues, adjacent normal tissues, and lymphatic tissues. (C) Bubble chart showing 5 typical genes expressed in each subtype. (D) UMAP plot of four subtypes colored in HSCC tissues, adjacent normal tissues, and lymphatic tissues. (E) Heatmap showing the top 10 marker genes of each subpopulation. (F) Exhausted effector CD8 T cells levels in HSCC tissues, adjacent normal tissues, and lymphatic tissues. (G) Exhausted NK T cells levels in HSCC tissues, adjacent normal tissues, and lymphatic tissues.