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[Preprint]. 2023 Jul 10:2023.07.09.548280. [Version 1] doi: 10.1101/2023.07.09.548280

Figure 2. Shared associations of gene deletion mutations with alcohol, methamphetamine, and nicotine use phenotypes.

Figure 2.

A) Bipartite graphs depicting significant effects of strain and strain × dose for consumption and preference of alcohol (EtOH), nicotine, and methamphetamine (MA). Significant associations are represented by the thickness of the edge connecting the two nodes. Edge weights are inversely proportional to the −log10 p-value of the association. B) Dose-response curve depicting the effect of Il12rb and Far2 deletions on EtOH preference. C) Dose-response curve depicting the effect of Il12rb and Far2 deletions on EtOH consumption. D) Dose-response curves depicting the effect of Il12rb and Far2 deletion on MA consumption. Data are shown as mean ± SD (FDR < 0.05).