Extended Data Fig. 9 |. Clustering of the phosphorylation dynamics following DNAJB1/PRKACA generation in HEK293T cells.
Protein phosphorylation dynamics in the HEK293T proteomics dataset are grouped into four clusters by the time of average maximum changes following induction of protein splicing. Relative phosphorylation levels in Cluster#1 members are maximally changed by 30 minutes, Cluster#2 members in 2 hours, Cluster#3 members in 6 hours, and Cluster#4 members in 12 hours. The members in each cluster were subcategorized into ‘UP- and DOWN-phosphorylated’ sites and proteins.