Figure 3. Beneficial genes vary widely by strain.

A) Hierarchical clustering of 314 genes that were beneficial in at least one strain (see Methods), as described in Figure 2; grey values indicate missing values. Several clusters were enriched for functional groups (p<1×10⁻⁴, Hypergeometric test) including genes involved in a) cell-cycle entry, c) negative regulation of heterochromatin, d) cytoplasmic mRNA processing body assembly, snoRNA processing. B) Overlap of beneficial genes identified in each strain.