Table 1.
Description and comparison of demographic and clinical characteristics of the patients between intervention and control groups
| Variable | Intervention group Frequency (%) n = 67 |
Control group Frequency (%) n = 66 |
p-value |
|---|---|---|---|
| Demographic characteristics | |||
| Age (year) | 58.83 ± 13.56 | 59.56 ± 13.27 | 0.677 |
| Gender | |||
| Male | 36 (49.5%) | 39 (50.5%) | 0.567† |
| Female | 31 (53.8%) | 27 (46.2%) | |
| Past medical history | |||
| Diabetes | 36 (48.0%) | 39 (52.0%) | 0.549† |
| Hypertension | 38 (52.1%) | 35 (47.9%) | 0.740† |
| Cardiovascular disease | 18 (48.6%) | 19 (51.4%) | 0.790† |
| Smoking | |||
| Cigarette | 8 (50.0%) | 8 (50.0%) | 0.961† |
| Hookah | 6 (50.0%) | 6 (50.0%) | 0.966† |
| Clinical parameters and Arterial Blood Gas | |||
| O2 Sat % | 86.79 ± 7.62 | 86.26 ± 6.64 | 0.352‡ |
| PaO2 mmHg | 49.05 ± 37.49 | 42.63 ± 17.33 | 0.044‡ |
| PCO2 mmHg | 46.67 ± 39.77 | 40.17 ± 10.16 | 0.039‡ |
| HCO3 mEq/L | 27.0 ± 9.54 | 24.37 ± 5.45 | 0.002‡ |
| Ph | 7.40 ± 0.08 | 7.39 ± 0.07 | 0.547‡ |
| Temperature | 37.12 ± 0.56 | 36.83 ± 2.07 | 0.081‡ |
| Calcium (mg/dL) | 8.57 ± 0.77 | 8.47 ± 0.82 | 0.269‡ |
| Phosphorus (mg/dL) | 4.02 ± 0.95 | 3.98 ± 1.09 | 0.755‡ |
| Magnesium (mg/dL) | 2.28 ± 0.27 | 2.25 ± 0.34 | 0.459‡ |
| Liver function tests and vitamin D | |||
| Vitamin D (ng/mL) | |||
| Baseline | 23.34 ± 18.47 | 23.07 ± 16.12 | 0.680‡ |
| After 1-month | 34.49 ± 17.51 | 28.17 ± 18.60 | 0.008‡ |
| ALT (U/L) | |||
| Baseline | 36.0 (21.0–68.0) | 35.0 (23.0–71.0) | 0.569‡ |
| After 1-month | 33.0 (16.0–43.0) | 29.0 (18.0–46.0) | 0.757‡ |
| AST (U/L L) | |||
| Baseline | 40.0 (26.7–63.5) | 37.0 (25.0–60.0) | 0.679‡ |
| After 1-month | 21.0 (16.0–28.0) | 21.0 (15.2–29.0) | 0.913‡ |
| ALP (U/L) | |||
| Baseline | 192.0 (158.0–277.5) | 182.5 (136.2–267.5) | 0.264‡ |
| After 1-month | 207.0 (172.5–249.7) | 219.5 (174.7–270.7) | 0.273‡ |
| GGT (IU/L) | |||
| Baseline | 48.0 (29.0–87.5) | 45.5 (26.2–77.5) | 0.401‡ |
| After 1-month | 12.0 (8.0–19.0) | 18.0 (10.0–33.0) | 0.010‡ |
| LDH (units/L) | |||
| Baseline | 432.0 (350.0–622.0) | 498.5 (359.2–632.7) | 0.379‡ |
| After 1-month | 359.0 (278.0–514.0) | 340.0 (303.0–429.0) | 0.833‡ |
†The chi square test was used for the comparison
‡Independent sample t-test or mann–whitney test was used for the comparison
ALT: Alanine Aminotransferase, AST: Aspartate Aminotransferase, GGT: Gamma-Glutamyl Transpeptidase, ALP: Alkaline Phosphatase, LDH: Lactate dehydrogenase