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[Preprint]. 2023 Jul 13:2023.07.13.548758. [Version 1] doi: 10.1101/2023.07.13.548758

Figure 5. Immune surveillance by microglia is unchanged after intravitreal injections with EGFP mRNA LNPs.

Figure 5.

Microglia distribution, labelled with Iba1, was compared for 4 different conditions: (A) no injection, (B) PBS intravitreal injection, (C) EGFP mRNA 2TLNP intravitreal injection, or (D) EGFP mRNA 6T LNP intravitreal injection. Microglia are present in similar patterns in the outer plexiform layer (OPL), inner plexiform layer (IPL), and GCL for all conditions 6 hours post-injection. Images shown are representative of at least 3 retinas and are MIPs (scale bar: 50 μM).