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[Preprint]. 2023 Nov 13:2023.07.12.548582. Originally published 2023 Jul 12. [Version 2] doi: 10.1101/2023.07.12.548582

Figure 4: Difference Woods plot of active-site and allosteric inhibitors relative to apo PTP1B.

Figure 4:

Difference in %deuteration values at 30 seconds in each inhibitor-bound state minus the apo PTP1B state, plotted against amino acid sequence. Blue lines indicate a difference interval of ± 5%.

A. Active-site inhibitor, TCS401.

B. Allosteric inhibitor, BB3.