TABLE 3.
Parameter | Units | Description | Input valuesb | Distribution | References |
---|---|---|---|---|---|
Log10(Cvirus) | PFU·mL−1 | Concn of virus in saliva | 6.80 (6.10, 7.40) | Triangular | 79, 103 |
FC | Cough·h−1 | Coughing rate per hour | 24.7 (10.0, 39.3) | Uniform | 104 |
Handsa | m2 | Surface area of two palms | 1.8 × 10−2 (1.5 × 10−2, 2.2 × 10−2) | Triangular | 105, 106 |
λhand | min−1 | Viral decay on hand surface | 1.20 (0.92, 1.47) | Uniform | 107 |
Freq.hs | Contact·min−1 | Contact frequency between hands and fomite | 8.4 (5.4, 11.4) | Triangular | 108 |
Freq.hf | Contact·min−1 | Contact frequency between hands and face | 0.261 (0.072, 0.450) | Triangular | 109 |
F 23 | Proportion | Proportion of virus transferred from hand to face | 0.200 (0.063) | Normal | 110 |
L dep | Proportion | Deposition fraction of virus into the lungs | 1.00 | Point | Assumed |
I R | m3·h−1 | Inhalation rate per hour | 2.40 (1.62, 3.18) | Uniform | 111 |
k risk c | PFU−1 | Dose-response parameter to determine infection risk at a given viral dose | 6.80 × 10−3 | Point | 80 |
QMRA, quantitative microbial risk assessment; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
The values presented as mode (minimum, maximum) for triangular distributions, mean (minimum, maximum) for uniform distributions, and mean (SD) for normal distributions.
This upper estimate, within the published krisk range (80), was used to calibrate our model to documented SARS-CoV-2 outbreaks, as described in the materials and methods.