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. 2023 Jun 13;89(7):e00128-23. doi: 10.1128/aem.00128-23

TABLE 3.

QMRA parameters for SARS-CoV-2 viral transmissiona

Parameter Units Description Input valuesb Distribution References
Log10(Cvirus) PFU·mL−1 Concn of virus in saliva 6.80 (6.10, 7.40) Triangular 79, 103
FC Cough·h−1 Coughing rate per hour 24.7 (10.0, 39.3) Uniform 104
Handsa m2 Surface area of two palms 1.8 × 10−2 (1.5 × 10−2, 2.2 × 10−2) Triangular 105, 106
λhand min−1 Viral decay on hand surface 1.20 (0.92, 1.47) Uniform 107
Freq.hs Contact·min−1 Contact frequency between hands and fomite 8.4 (5.4, 11.4) Triangular 108
Freq.hf Contact·min−1 Contact frequency between hands and face 0.261 (0.072, 0.450) Triangular 109
F 23 Proportion Proportion of virus transferred from hand to face 0.200 (0.063) Normal 110
L dep Proportion Deposition fraction of virus into the lungs 1.00 Point Assumed
I R m3·h−1 Inhalation rate per hour 2.40 (1.62, 3.18) Uniform 111
k risk c PFU−1 Dose-response parameter to determine infection risk at a given viral dose 6.80 × 10−3 Point 80
a

QMRA, quantitative microbial risk assessment; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

b

The values presented as mode (minimum, maximum) for triangular distributions, mean (minimum, maximum) for uniform distributions, and mean (SD) for normal distributions.

c

This upper estimate, within the published krisk range (80), was used to calibrate our model to documented SARS-CoV-2 outbreaks, as described in the materials and methods.