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. Author manuscript; available in PMC: 2023 Jul 26.
Published in final edited form as: Vaccine. 2021 Mar 6;39(14):1897–1909. doi: 10.1016/j.vaccine.2021.02.059

Table 3.

Criteria for decision-making included in the framework articles and related studies* (n = 72), systematic review of national decision-making 2010–2020.

Category Criteria Frameworks including criterion (n = 27) Studiesa mentioning criterion (n = 45)
% (n) Total n of articles including at least one criteria of the category % (n) Total n of articles including at least one criteria of the category
Vaccine characteristics Efficacy/effectiveness 96 (26) (n = 27) 93 (41) (n = 44)
Vaccine safety 93 (25) 80 (35)
Delivery issues 41 (11) 66 (29)
Other characteristics 37 (10) 30 (13)
The importance of the health problem Burden of disease 100 (26) (n = 26) 95 (40) (n = 42)
Political priority 31 (8) 62 (26)
Costs of disease 50 (13) 40 (17)
Perceptions of importance 38 (10) 38 (16)
Other 23 (6) 14 (6)
Financial/economic issues Economic evaluation 96 (25) (n = 26) 83 (34) (n = 41)
Incremental costs 27 (7) 20 (8)
Funding sources 12 (3) 46 (19)
Vaccine price 62 (16) 51 (21)
Financial sustainability 31 (8) 32 (13)
Other (including affordability) 35 (9) 29 (12)
Consideration of alternative interventions Cost-effectiveness of alternatives 96 (24) (n = 25) 100 (35) (n = 35)
Effectiveness of alternatives 40 (10) 34 (12)
Other considerations 16 (4) 3 (1)
Decision-making process Evidence sources/quality of evidence 75 (18) (n = 24) 61 (23) (n = 38)
Stakeholders involved 67 (16) 89 (34)
Procedures 42 (10) 66 (25)
Cues to action 14 (4) 29 (11)
Impact of vaccination Impact on health outcomes 90 (19) (n = 21) 93 (28) (n = 30)
Impact on non-health outcomes 67 (14) 67 (20)
Effects of coadministration 5 (1) 23 (7)
Risks of serotype replacement 19 (4) 20 (6)
Other impact 0 (0) 3 (1)
Programmatic considerations Feasibility 73 (11) (n =15) 50 (13) (n = 26)
Vaccine supply 47 (7) 69 (18)
Acceptability Acceptability of vaccine 100 (11) (n = 11) 100 (20) (n = 20)
Accessibility, equity and ethics Accessibility, equity and ethics 100 (13) (n = 13) 100 (15) (n = 15)
*

Article type 1, Frameworks and article type 2, Studies that collect or analyze empirical data on vaccine adoption decision-making and examples of vaccine adoption decision-making.

a

Studies include the 31 articles that collected empirical data on decision-making and the 14 examples of vaccine introduction decision-making.