Table 1.
| Clinical Variable | Older | Younger | P value |
|---|---|---|---|
| Age (years) | 74 ± 7 | 26 ± 3 | 1.19E −10 |
| Sex (F/M) | 5/5 | 5/5 | |
| Race (WH/BL/AI/UNK) | (8/1/0/1) | (7/2/1/0) | |
| Ethnicity (NH/H/UNK) | (5/1/4) | (2/5/3) | |
| BMI (kg/m2) | 29.38 ± 4.78 | 28.31 ± 4.80 | 0.623 |
| Waist (cm) | 102.69 ± 13.39 | 90.81 ± 8.07 | 0.0272 |
| Waist-to-hip Ratio | 0.96 ± 0.11 | 0.86 ± 0.08 | 0.0252 |
| SBP (mmHg) | 136 ± 13 | 122 ± 9 | 0.0256 |
| DBP (mmHg) | 78 ± 8 | 72 ± 7 | 0.109 |
| Glucose (mg/dL) | 97.50 ± 15.71 | 89.39 ± 7.23 | 0.151 |
| Insulin (μIU/mL) | 13.52 ± 7.36 | 11.34 ± 6.20 | 0.497 |
| HbAlc (%) | 5.63 ± 0.27 | 5.26 ± 0.54 | 0.0694 |
| Cholesterol (mg/dL) | 187.90 ± 43.51 | 151.20 ± 26.37 | 0.0349 |
| LDL (mg/dL) | 111.30 ± 42.58 | 80.60 ± 26.68 | 0.0692 |
| VLDL (mg/dL) | 21.10 ± 8.35 | 13.20 ± 6.32 | 0.0406 |
| HDL (mg/dL) | 55.50 ± 11.32 | 57.40 ± 12.20 | 0.722 |
| Non-HDL Cholesterol (mg/dL) | 132.40 ± 44.76 | 93.80 ± 24.53 | 0.0279 |
| Triglycerides (mg/dL) | 104.90 ± 41.95 | 66.10 ± 31.80 | 0.0316 |
| FFA (mmol/L) | 0.26 ± 0.14 | 0.34 ± 0.20 | 0.374 |
| ADIPO-IR | 0.56 ± 0.33 | 0.69 ± 0.52 | 0.522 |
| TSH (μIU/mL) | 2.59 ± 1.19 | 1.52 ± 0.78 | 0.0279 |
| ALT (units/L) | 20.00 ± 3.13 | 26.90 ± 28.47 | 0.361 |
| AST (units/L) | 26.00 ± 2.16 | 25.70 ± 19.56 | 0.0278 |
| CRP (mg/L) | 2.43 ± 1.61 | 2.68 ± 2.82 | 1 |
Abbreviations: ADIPO-IR, Adipose Tissue Insulin Resistance Index; AI, American Indian; ALT, Alanine Transaminase; AST, Aspartate Aminotransferase; BL, Black; BMI, Body Mass Index; CRP, C-Reactive Protein; DBP, Diastolic Blood Pressure; F, Female; FFA, Free-fatty Acid; H, Hispanic; HbA1c, Hemoglobin A1C; HDL, High-Density Lipoprotein; LDL, Low-Density Lipoprotein; M, Male; NH, Non-Hispanic; SBP, Systolic Blood Pressure; TSH, Thyroid Stimulating Hormone; WH, White; UNK, unknown;