Figure 2.
FDR-significant (FDR < 0.05) differentially methylated positions associated with aortic augmentation index. a) Multi-ancestry epigenome-wide association studies (EWAS) summary statistics of two FDR-significant CpGs. b) Forest plots of race-stratified EWAS of two FDR-significant CpGs. Position, based on GRCh38/hg38; Estimate (se) and P-value, effect size (standard error) and p-value of CpG respectively from EWAS; FDR, false discovery rate based on multiple testing correction on 491,174 CpGs; NHW, Non-Hispanic White; AA, African American; HIS, Hispanic/Latino.