Table 3.
Multiple linear regression analyses evaluating the influence of exposure measures on medial temporal MRI and neurobehavioral metrics for exposed subjects
| Outcome variables | Selected Predictors | Linear β | T-value | p-value |
|---|---|---|---|---|
|
| ||||
| Exposed subjects (N=42) | ||||
|
| ||||
| Metal exposure history | ||||
|
| ||||
| Parahippocampal FA | YrsW | −0.001 | −2.61 | 0.013 |
| Hippocampal RD | ELT | 0.021 | 2.06 | 0.046 |
| Symbol-Digit Coding | E90 | −0.163 | −2.54 | 0.015 |
|
| ||||
| Blood Metal Levels | ||||
|
| ||||
| Entorhinal MD | Mn | 0.163 | 2.14 | 0.040 |
|
| ||||
| Entorhinal AD | Mn | 0.180 | 2.16 | 0.038 |
|
| ||||
| Entorhinal RD | Mn | 0.153 | 2.11 | 0.043 |
|
| ||||
| Entorhinal FA | Pb | 0.013 | 2.13 | 0.040 |
|
| ||||
| Hippocampal AD | Fe | −0.337 | −2.33 | 0.027 |
|
| ||||
| Phonemic Fluency | Pb | −0.572 | −2.13 | 0.041 |
|
| ||||
| Trail Making-B | Zn | 4.657 | 2.78 | 0.009 |
|
| ||||
| List Learning | Fe | 4.713 | 2.41 | 0.022 |
|
| ||||
| Immediate Story Recall | Cu | −3.779 | −2.50 | 0.018 |
|
| ||||
| Delayed Story Recall | Cu | −3.881 | −2.87 | 0.007 |
Data represent parameter estimates and corresponding T- and p-values of exposure measurements to predict MTL MRI and neurobehavioral metrics.