Table 3.
Total burden model of minor alleles for dispatched RND transporter family member 1 toll-like receptor 5 variants, rs17538288 >A and rs7546189 >T.
| Number of Minor Alleles, (Number of Patients) | 0 (n=318) | 1 (n=318) | 2 (n=449) | 3 (n=178) | 4 (n=100) | Risk of AKI (OR, 95% CI) | P Value |
|---|---|---|---|---|---|---|---|
| AKI, n (%) | 119 (37%) | 136 (43%) | 213 (47%) | 102 (57%) | 67 (67%) | 1.34 (1.22 to 1.48) | 1.77×10−9 |
| No AKI, n (%) | 205 (63%) | 182 (57%) | 236 (53%) | 76 (43%) | 33 (33%) | — | — |
Zero designates homozygous major allele for both variants, and four designates homozygous minor allele for both variant. RND, resistance-nodulation-division; OR, odds ratio; CI, confidence interval.