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. 2023 Mar 7;14(7):e00578. doi: 10.14309/ctg.0000000000000578

Table 3.

Top 20 genes that correlate with stool frequency or bowel urgency

Top 20 genes correlated with stool frequency Top 20 genes correlated with bowel urgency
Symbol Name tau Symbol Name tau
S100A8 S100 calcium binding protein A8 0.379 CCDC175 Coiled-coil domain containing 175 −0.297
S100A12 S100 calcium binding protein A12 0.371 TNFRSF17 TNF receptor superfamily member 17 0.277
CDHR1 Cadherin-related family member 1 −0.370 CFB Complement factor B 0.273
S100A9 S100 calcium binding protein A9 0.363 FBXW7 F-box and WD repeat domain containing 7 0.271
TRIB2 Tribbles pseudokinase 2 0.360 LIPA Lipase A, lysosomal acid type 0.269
PTAFR Platelet-activating factor receptor 0.359 CEP128 Centrosomal protein 128 0.268
AIFM3 Apoptosis-inducing factor mitochondria associated 3 −0.359 BIRC3 Baculoviral IAP repeat containing 3 0.267
FCGR3B Fc fragment of IgG receptor IIIb 0.357 IFNAR2 Interferon alpha and beta receptor subunit 2 0.267
CSF3R Colony-stimulating factor 3 receptor 0.356 PSAT1 Phosphoserine aminotransferase 1 0.267
LYN LYN proto-oncogene, Src family tyrosine kinase 0.356 SNX25 Sorting nexin 25 0.266
IFITM2 Interferon-induced transmembrane protein 2 0.356 HSPA13 Heat shock protein family A (Hsp70) member 13 0.263
CAPN13 Calpain 13 −0.356 CLDN2 Claudin 2 0.263
ELL2 Elongation factor for RNA polymerase II 2 0.356 LY96 Lymphocyte antigen 96 0.262
PROK2 Prokineticin 2 0.355 SEC11C SEC11 homolog C, signal peptidase complex subunit 0.261
AQP9 Aquaporin 9 0.355 DRAM1 DNA damage-regulated autophagy modulator 1 0.260
IL1A Interleukin 1 alpha 0.355 CPEB4 Cytoplasmic polyadenylation element-binding protein 4 0.260
FCGR2A Fc fragment of IgG receptor IIa 0.354 PCK1 Phosphoenolpyruvate carboxykinase 1 −0.259
TIMP1 TIMP metallopeptidase inhibitor 1 0.354 ELL2 Elongation factor for RNA polymerase II 2 0.259
TCN1 Transcobalamin 1 0.353 CTSH Cathepsin H 0.259
CKB Creatine kinase B −0.353 CAPN13 Calpain 13 −0.259

Top 20 genes correlated with stool frequency or bowel urgency. Tau value (Kendall rank correlation) indicates the strength of correlation.