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. 2023 May 29;14(7):e00602. doi: 10.14309/ctg.0000000000000602

Table 2.

Healing rates of duodenal ulcers

Keverprazan Lansoprazole
Week 6
 Full analysis set n = 180 n = 178
 No. (%) of healed patients 170 (94.4) 166 (93.3)
 Difference from LPZ with 95% CI 1.19 (−4.0, 6.5)
P Value 0.6404
Per protocol set n = 166 n = 167
 No. (%) of healed patients 163 (98.2) 163 (97.6)
 Difference from LPZ with 95% CI 0.6 (−3.1, 4.4)
P Value 1.0000
Week 4
 Full analysis set n = 180 n = 178
 No. (%) of healed patients 151 (83.9) 143 (80.3)
 Difference from LPZ with 95% CI 3.6 (−4.5, 11.6)
P Value 0.3805
Per protocol set n = 166 n = 167
 No. (%) of healed patients 144 (86.8) 143 (85.6)
 Difference from LPZ with 95% CI 1.1 (−6.4, 8.7)
P Value 0.7675

Noninferiority was assessed using the Miettinen-Nurminen method with a noninferiority margin of −8%.

LPZ, lansoprazole.